Wash your hands well with soap and warm water for at least 20 seconds.
Line a baking pan with aluminum foil and coat with cooking spray.
Drain salmon, remove skin and bones and break into small pieces in a medium mixing bowl.
Tear bread slice into small pieces and add to mixing bowl.
Wash and cut bell pepper and celery and cut into small pieces. Peel and cut onion into small pieces. Add bell pepper, celery, and onion to the mixing bowl.
Crack eggs into a small bowl and mix with a fork or whisk until lightly beaten. Add eggs to the mixing bowl with all other ingredients.
Add lemon juice, mayonnaise, and red pepper flakes to the mixing bowl and mix ingredients well.
Use your hands to form 6 patties and place on the baking pan. Place baking pan in the oven on bottom rack and cook for 15 minutes, then turn and cook for an additional 15 minutes or until patties are golden brown.